The hands and wrists are made up of multiple small joints. Arthritis can occur when the cartilage in these areas is destroyed, causing the bones of the hand and wrist to rub against each other.

Signs and symptoms of arthritis in the hands or wrists include pain, stiffness, and inflammation. Other common symptoms of this condition include swelling, weakness, a limited range of motion, and audible clicking sounds that occur when moving the hand or wrist.